Category: Streptococcus pneumoniae

Laboratory diagnosis, Treatment and Prevention of Streptococcus pneumoniae 4.8/5 (10)

Laboratory diagnosis, Treatment and Prevention of Streptococcus pneumoniae

Laboratory diagnosis of Streptococcus pneumoniae Specimen: Sputum, blood, endotracheal aspirate, bronchoalveolar lavage, cerebrospinal fluid (CSF), pleural fluid, joint fluid, abscess fluid, bones, and other biopsy material. Microscopy Gram staining of sputum shows lancet shaped Gram-positive cocci in pairs. Fresh emulsified sputum mixed with antiserum causes capsule swelling (the quellung reaction) for identification of pneumococci. In […]

Virulence factors, Pathogenesis and Clinical manifestations of Streptococcus pneumoniae 4.44/5 (9)

Virulence factors, Pathogenesis and Clinical manifestations of Streptococcus pneumoniae

Virulence factors of Streptococcus pneumoniae Polysaccharide capsule The capsule is antiphagocytic, inhibiting complement deposition and phagocytosis. 2. Cell wall associated polymers and proteins Teichoic acid – binds to epithelial cells and activates alternative complement pathway Protein adhesion – binds to epithelial cells Peptidogylcan – activates alternative complement pathway Phosphorylcholine – mediates invasion of host cell […]

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